Recent Changes

Friday, August 18

  1. page Required Lab Safety edited Spring Fall 2017 Lab DUE DATE: : Prior to beginning your second wet lab– bring printout to la…

    SpringFall 2017 Lab
    DUE DATE: : Prior to beginning your second wet lab– bring printout to lab. LAST DAY TO TURN IN: Monday, 1/23/17 at 11:59PM
    Finish your training
    (view changes)
    11:23 am

Thursday, August 3

  1. page Targets edited ... TargetF15 - S-adenosylmethionine Synthetase (Burkholderia pseudomallei).......................…
    ...
    TargetF15 - S-adenosylmethionine Synthetase (Burkholderia pseudomallei)......................................Matthew N., Justin H.
    Target - Protein Tyrosine Phosphatase (Listeria monocytogenes) ------- Akhilesh, Mihir, Shane
    Target -1-deoxy-D-xylulose 5-phosphate reductoisomerase (Francisella Tularensis)----------Janice, Aldo
    New
    D-alanine ligase (Yersinia pestis)........................................................................................Su17 - Rosa J, Allison P, Nihitha
    6-phosphoglucanate dehydrogenase (//T. gondii//)................................................................... Su17 - Quynh (Megan) L, Orlando, Shaochen (Tiger) Y
    Not used
    D-alanine ligase (//K. pneumoniae//).........................................................................................Tiger Y.- not enough info for a target
    6-phosphoglucanate dehydrogenase (//L. monocytogenes//)...................................................Kaan K.- Not enough info on essentiality
    Target -1-deoxy-D-xylulose 5-phosphate reductoisomerase (Francisella Tularensis)----------Janice, Aldo
    TargetSp17- PP2C- family Ser Thr Phosphatase (Mycobacterium tuberculosis)...Cecilia Williams - good - Dr .B
    TargetSp17 - Inogranic pyrophosphatase (Burkholderia pseudomallei) . . . . . Vivian C. good Dr. B
    (view changes)
    10:03 am

Tuesday, July 25

  1. page Targets edited ... Revivals Not Cloned yet ... W, Parthavi M M, Marcus H. TargetF15 - D-alanine Ligase (L…
    ...
    Revivals
    Not Cloned yet
    ...
    W, Parthavi MM, Marcus H.
    TargetF15 - D-alanine Ligase (Listeria monocytogenes).....................................................................Simone M. Su17 - Edd E., Esther J., Zohair A
    TargetF15 - 6-phosphoglucanate dehydrogenase, decarboxylating, putative (Trypanosoma cruzi)...Diane C. Su17 - Kaan K, Sung-Hoon P, Patricia B,
    (view changes)
    10:00 am

Sunday, July 23

  1. page Journal Club Summer 17 edited ... Week 8: Jul-24 Monday - Jul-30 Sunday For dates See Main Summer 17 page Week 7 5th 8 6th…
    ...
    Week 8: Jul-24 Monday - Jul-30 Sunday
    For dates See Main Summer 17 page
    Week 7
    5th
    8
    6th
    Paper
    Prasannan, P.; Suliman, H. S.; Robertus, J. D., Kinetic analysis

    Herschhorn, A.; Hizi, A., Virtual screening, identification, and biochemical characterization
    of site-directed mutantsnovel inhibitors of methionine synthase from Candida albicans. Biochem Biophys Res Commun 2009, 382 (4), 730-4.
    PrasannanPriya_MetSynthaseKinetic_RobertusBiochemBiophysResComm2009.pdf {PrasannanPriya_MetSynthaseKinetic_RobertusBiochemBiophysResComm2009.pdf}
    the reverse transcriptase of human immunodeficiency virus type-1. J Med Chem 2008, 51 (18), 5702-13.
    HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf {HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf}

    Reading Strategies for Journal Articles
    First pass - Skim Abstract, Conclusions, Figures
    ...
    Put slide numbers on the slides
    See Fall Journal Club Page for more Guidelines about other presentations (e.g. Research or Technical Presentations)
    Week 8
    6th Paper
    Herschhorn, A.; Hizi, A., Virtual screening, identification, and biochemical characterization of novel inhibitors of the reverse transcriptase of human immunodeficiency virus type-1. J Med Chem 2008, 51 (18), 5702-13.
    HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf {HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf}

    Week 9
    7th Paper
    ...
    Cho, Y.; Ioerger, T.; Sacchettini, J., Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening. J Med Chem 2008, 51 (19), 5984-92.
    ChoSacchettiniVirtualScreening_TB_HisG_JMedChem2008.pdf
    Week 7
    5th Paper
    Prasannan, P.; Suliman, H. S.; Robertus, J. D., Kinetic analysis of site-directed mutants of methionine synthase from Candida albicans. Biochem Biophys Res Commun 2009, 382 (4), 730-4.
    PrasannanPriya_MetSynthaseKinetic_RobertusBiochemBiophysResComm2009.pdf {PrasannanPriya_MetSynthaseKinetic_RobertusBiochemBiophysResComm2009.pdf}

    (view changes)
    7:35 pm

Tuesday, July 18

  1. page Targets edited ... Is my target good for Virtual Screening programs? Reynolds_THermodynamicsLigandBinding_MedChe…
    ...
    Is my target good for Virtual Screening programs?
    Reynolds_THermodynamicsLigandBinding_MedChemLett2011.pdf {Reynolds_THermodynamicsLigandBinding_MedChemLett2011.pdf}
    UT Libraries Pages
    Biomedical Big Data Resource Center
    Biochemistry (Bioinformatics and Cheminformatics Tools)

    Dr. B
    Link to other page
    (view changes)
    4:47 pm

Monday, July 17

  1. page Kian C. edited SensoLyte® pNPP Protein Phosphatase Assay Kit *Colorimetric* -Note: activity assay kit to use later…
    SensoLyte® pNPP Protein Phosphatase Assay Kit *Colorimetric* -Note: activity assay kit to use later
    Week 7 & 8
    Mutant DNA Analysis
    {EhMut125-126_orderresults.png}
    {EhMut125-126_sequenced.png}

    Week 5 & 6
    DH5α Transformation with Mutant EhPTP pNIC-Bsa4
    (view changes)
    2:29 pm

Sunday, July 16

  1. page Journal Club Summer 17 edited ... Put slide numbers on the slides See Fall Journal Club Page for more Guidelines about other pr…
    ...
    Put slide numbers on the slides
    See Fall Journal Club Page for more Guidelines about other presentations (e.g. Research or Technical Presentations)
    Week 68
    6th Paper
    Herschhorn, A.; Hizi, A., Virtual screening, identification, and biochemical characterization of novel inhibitors of the reverse transcriptase of human immunodeficiency virus type-1. J Med Chem 2008, 51 (18), 5702-13.
    HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf {HerschhornHIVreversetranscriptaseVirtualScreenJMedChem2008.pdf}
    Week 79
    7th Paper
    Hirayama, K.; Aoki, S.; Nishikawa, K.; Matsumoto, T.; Wada, K., Identification of novel chemical inhibitors for ubiquitin C-terminal hydrolase-L3 by virtual screening. Bioorg Med Chem 2007, 15 (21),
    6810-8.
    VDS_UBL3_bioorgmedchem2007.pdf {VDS_UBL3_bioorgmedchem2007.pdf}
    Week 8
    8th Paper
    ??

    Potential Papers:
    Singh, J.; Chuaqui, C.; Boriack-Sjodin, P.; Lee, W.; Pontz, T.; Corbley, M.; Cheung, H.; Arduini, R.; Mead, J.; Newman, M.; Papadatos, J.; Bowes, S.; Josiah, S.; Ling, L., Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI). Bioorg Med Chem Lett 2003, 13 (24), 4355-9.
    (view changes)
    7:41 pm
  2. page Journal Club Summer 17 edited ... Week 8: Jul-24 Monday - Jul-30 Sunday For dates See Main Summer 17 page Week 5 7 5th Pap…
    ...
    Week 8: Jul-24 Monday - Jul-30 Sunday
    For dates See Main Summer 17 page
    Week 57
    5th Paper
    Prasannan, P.; Suliman, H. S.; Robertus, J. D., Kinetic analysis of site-directed mutants of methionine synthase from Candida albicans. Biochem Biophys Res Commun 2009, 382 (4), 730-4.
    (view changes)
    7:40 pm

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