Targets+-+OLD+stuff

OLD STUFF


 * Sadhana**

m Protocol Target Discovery ORGANISM: MYCOBACTERIUM TUBERCULOSIS H37Rv EC# 3.1.3.16 TARGET ENZYME: protein-tyrosine-phosphatase GENE OF INTEREST: ppp serine/threonine phosphatase NCBI GENE # OR REFSEQ #:887070 CDS GENE SEQUENCE: >gi|57116681:c23181-21637 Mycobacterium tuberculosis H37Rv, complete genome GTGGCGCGCGTGACCCTGGTCCTGCGATACGCGGCGCGCAGCGATCGCGGCTTGGTACGCGCCAACAACGAAGACTCGGTCTACGCTGGGGCACGGCTATTGGCCCTGGCCGACGGCATGGGTGGGCATGCGGCCGGCGAGGTGGCGTCCCAGTTGGTGATTGCCGCATTGGCCCATCTCGATGACGACGAGCCCGGTGGCGATCTGCTGGCCAAGCTGGATGCCGCGGTGCGCGCCGGCAACTCGGCTATCGCAGCGCAAGTCGAGATGGAGCCCGATCTCGAAGGCATGGGTACCACGCTCACCGCAATCCTGTTCGCGGGCAACCGGCTCGGCCTGGTGCATATCGGTGACTCGCGCGGTTACCTGCTGCGCGACGGTGAGCTGACGCAGATCACCAAGGACGACACGTTTGTCCAA ACGCTGGTCGACGAAGGCCGGATCACCCCGGAGGAGGCGCACAGCCACCCGCAACGCTCGTTGATCATGCGGGCGTTGACCGGCCATGAGGTCGAACCGACGCTGACCATGCGAGAAGCCCGCGCCGGTGATCGTTACCTGCTGTGCTCGGACGGGTTGTCCGATCCGGTTAGCGATGAAACTATCCTCGAGGCCCTGCAGATCCCCGAGGTTGCCGAGAGCGCTCACCGCCTCATTGAACTGGCGCTGCGCGGCGGCGGCCCCGACAACGTCACTGTCGTCGTCGCCGACGTCGTCGACTACGACTACGGCCAGACCCAACCGATTCTGGCCGGGGCGGTCTCAGGCGACGACGACCAACTGACCCTGCCCAACACCGCCGCCGGCCGGGCCTCTGCCATCAGCCAGCGCAAGGAGATCGTTAAACGCGTTCCGCCACAGGCCGATACATTCAGTCGGCCACGGTGGTCGGGCCGACGGCTAGCATTCGTTGTCGCACTGGTGACCGTGCTGATGACTGCGGGCCTGCTCATTGGTCGCGCGATCATCCGCAGCAACTACTACGTAGCGGACTACGCCGGCAGCGTGTCCATCATGCGGGGGATTCAAGGGTCGCTACTGGGCATGTCCCTGCACCAGCCTTACCTGATGGGCTGCCTCAGCCCGCGTAACGAGCTGTCGCAGATCAGCTACGGACAGTCTGGGGGCCCTCTCGACTGCCATCTGATGAAACTGGAGGATCTGCGACCGCCGGAGCGCGCACAGGTTCGGGCCGGTCTCCCGGCCGGCACTCTCGATGACGCCATCGGGCAGTTGCGCGAACTGGCGGCCAACTCCCTG CTGCCGCCTTGCCCGGCGCCGCGTGCCACGTCCCCGCCCGGGCGCCCGGCCCCACCCACCACCAGCGAGACAACCGAACCAAACGTCACCTCCTCGCCAGCCTCTCCATCACCCACCACCTCCGCGCCGGCCCCCACCGGAACTACTCCTGCCATCCCCACGAGTGCCTCCCCGGCAGCGCCCGCGTCGCCGCCGACGCCTTGGCCCGTCACCAGCTCGCCGACGATGGCCGCACTTCCGCCACCCCCGCCTCAGCCGGGCATCGACTGCCGGGCGGCGGCATGA

AMINO ACID SEQUENCE: >1TXO:A|PDBID|CHAIN|SEQUENCE

MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD

PDB STRUCTURE IDENTIFIER: 2CM1

__**Joshua**__

ORGANISM: Mycobacterium tuberculosis H37Rv EC# of Enzyme: 3.1.3.16 GENE of INTEREST:  ppp serine/threonine phosphatase NCBI GENE #: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;"> 887070 CDS GENE SEQUENCE: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">>gi|57116681:c23181-21637 Mycobacterium tuberculosis H37Rv, complete genome <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">GTGGCGCGCGTGACCCTGGTCCTGCGATACGCGGCGCGCAGCGATCGCGGCTTGGTACGCGCCAACAACGAAGACTCGGTCTACGCTGGGGCACGGCTATTGGCCCTGGCCGACGGCATGGGTGGGCATGCGGCCGGCGAGGTGGCGTCCCAGTTGGTGATTGCCGCATTGGCCCATCTCGATGACGACGAGCCCGGTGGCGATCTGCTGGCCAAGCTGGATGCCGCGGTGCGCGCCGGCAACTCGGCTATCGCAGCGCAAGTCGAGATGGAGCCCGATCTCGAAGGCATGGGTACCACGCTCACCGCAATCCTGTTCGCGGGCAACCGGCTCGGCCTGGTGCATATCGGTGACTCGCGCGGTTACCTGCTGCGCGACGGTGAGCTGACGCAGATCACCAAGGACGACACGTTTGTCCAA <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">ACGCTGGTCGACGAAGGCCGGATCACCCCGGAGGAGGCGCACAGCCACCCGCAACGCTCGTTGATCATGCGGGCGTTGACCGGCCATGAGGTCGAACCGACGCTGACCATGCGAGAAGCCCGCGCCGGTGATCGTTACCTGCTGTGCTCGGACGGGTTGTCCGATCCGGTTAGCGATGAAACTATCCTCGAGGCCCTGCAGATCCCCGAGGTTGCCGAGAGCGCTCACCGCCTCATTGAACTGGCGCTGCGCGGCGGCGGCCCCGACAACGTCACTGTCGTCGTCGCCGACGTCGTCGACTACGACTACGGCCAGACCCAACCGATTCTGGCCGGGGCGGTCTCAGGCGACGACGACCAACTGACCCTGCCCAACACCGCCGCCGGCCGGGCCTCTGCCATCAGCCAGCGCAAGGAGATCGTTAAACGCGTTCCGCCACAGGCCGATACATTCAGTCGGCCACGGTGGTCGGGCCGACGGCTAGCATTCGTTGTCGCACTGGTGACCGTGCTGATGACTGCGGGCCTGCTCATTGGTCGCGCGATCATCCGCAGCAACTACTACGTAGCGGACTACGCCGGCAGCGTGTCCATCATGCGGGGGATTCAAGGGTCGCTACTGGGCATGTCCCTGCACCAGCCTTACCTGATGGGCTGCCTCAGCCCGCGTAACGAGCTGTCGCAGATCAGCTACGGACAGTCTGGGGGCCCTCTCGACTGCCATCTGATGAAACTGGAGGATCTGCGACCGCCGGAGCGCGCACAGGTTCGGGCCGGTCTCCCGGCCGGCACTCTCGATGACGCCATCGGGCAGTTGCGCGAACTGGCGGCCAACTCCCTG <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">CTGCCGCCTTGCCCGGCGCCGCGTGCCACGTCCCCGCCCGGGCGCCCGGCCCCACCCACCACCAGCGAGACAACCGAACCAAACGTCACCTCCTCGCCAGCCTCTCCATCACCCACCACCTCCGCGCCGGCCCCCACCGGAACTACTCCTGCCATCCCCACGAGTGCCTCCCCGGCAGCGCCCGCGTCGCCGCCGACGCCTTGGCCCGTCACCAGCTCGCCGACGATGGCCGCACTTCCGCCACCCCCGCCTCAGCCGGGCATCGACTGCCGGGCGGCGGCATGA

AMINO ACID SEQUENCE: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">>2CM1:A|PDBID|CHAIN|SEQUENCE <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">MGSSHHHHHHSSGLVPRGSHMARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD

PDB Structure Identifier: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 11pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">2CM1

ORGANISM: GENE of INTEREST: NCBI GENE # or RefSeq#: EC# of Enzyme: CDS GENE SEQUENCE: AMINO ACID SEQUENCE:
 * Hong**

__**Jeanette**__ ORGANISM: Trypanosoma brucei GENE of INTEREST: acid phosphatase **(Not enough similarity to a PDB structure)** NCBI GENE # or RefSeq#: 3661968 EC# of Enzyme: 3.1.3.2 CDS GENE SEQUENCE: >gi|73747658:1747242-1748549 Trypanosoma brucei TREU927 chromosome 10, complete genome

ATGTTCCTTTTGCCAAGGGAAGTAATGAGGAAGTACGCCATATTTTCCTTAGCAATCATACTGTTGCTAT

TTACAGTAGTGAGCAGTGAGCCTGGTGAGCGCGATGCGGAGTCCGGGGTGAAGAGAGGGGACGAAAAGCA

GAACCTCGTCCTCACTAAGCTAATTGTTCTCAACCGTCATGGTCACCGCGCCCCTAACGCCCCCTACTGG

TCCATGTGCCCCAACGACAGAAAAAACCGCCGCAAGTACAACGTTGGCGCGGAGGACCTTACGGCGCGCG

GCATGAAGGAGGAGTATGAATTGGGGGAGTATTTACGGAACGCGTATCGCGACTTTATTGGACCTCGCTT

CAACCGAAGTCGGCACTTCCTGCGCGCCGTGGGCGAACCCCGAATTCTGCAGTCCGCTCAGGCGGTTGCC

CAAGGGCTCTTTCCTGATGGTTATGGGCCCGGTGGCTATCTTCCGCGACAACCTCAGTTTGTGCCCGTAT

TTTCTGATATGGATACTCATGAATATCTTCTCGACGACGTACCGTGCTTCCGCCGCGCTGAGAGGGATAT

GCGCAGATGGTTGAACACTAGCTTGAGTGACTTCATTGCTGACCCTAAAGTCAGCGAGGTGTTAAACTAT

ATGAAACGGATGTGTGGGGTGTCTGAGAAGGACATGCCACCCGTATATGCTTTTCTGAAAACTGTAGCCG

ACGGGATGACATTCAATGCCGATTTCGGACTGAGCGTGTGCCATGGGAAGGTAACACCCGAAATGCTCTT

CAAAATACGCAAAGTATCACTACGACTTCTTATGGCGCGACTTTATCACACTGACGAGCAACAAACCTAC

ACCTCTGTAGATTTACCATACCGGATACTCTATATGCTAAATCGGTCAACCTCCCCAGGTGCGAAGGGAG

TGAACGATTACTCCGACACAGAGCAGGAAGCCATCCTGTATTTTATGCATCGCGAGGCCCTGTACGCTGT

TGGAGAGTTCTTTGGTTTCACATTTAATGTCCCAGGTCTGCCGCACGGGGAGCTGCCAGTGGCTTCTACA

ATTGTATGGGAGCGGTTGGTTCCTGAGAAGAGCGTCGGGGAAGAGATTGTGCCATCAAGAACGTACGTGC

GTCTCATACTATGGACACCAAAGGATGGTACAGCCACGGTTGCCATACCGCACTGCAGAACACCCCAGCT

TTGCACACTCAAAGAACTTCAGGATATATACAGTGCGCGGGTGAAGCGCACTGGATCGTGGTTGAAGCTG

TGCAACTTCACAATCACAGAATTAGACCATGACACGGACATTCGTTAG AMINO ACID SEQUENCE:

Marshall ORGANISM: GENE of INTEREST: NCBI GENE # or RefSeq#: EC# of Enzyme: CDS GENE SEQUENCE: AMINO ACID SEQUENCE:

Bubonic Plague <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">caused by bacteria Yersinia Pestis <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">EC 3.6.1.11 <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">Structure of Exopolyphosphatase from Yersinia pestis <[]>

<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">African Sleeping Sickness <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">caused by protozoan Trypanosoma brucei <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">pdb number 3M4U <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">EC 3.1.3.48 Enzyme is<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;"> Protein-Tyrosine-Phosphatase <[]>

__**Justin**__ ORGANISM: Toxoplasma gondii ME49 GENE of INTEREST: TGME49_031850 (serine-threonine phosophatase 2C)

NCBI GENE # or RefSeq#: 7898899 EC# of Enzyme:3.1.3.16

CDS GENE SEQUENCE: code format="genbank" 1 atgaagtcct ctgctgaaat taggcggacc atggatgtcc ctcctaccat tcatgtacct 61 ctccctccaa cgtcgtatcc cgctttcgat gctgcgatct tcacagacat cggtgggcgc 121 aagcatcagg aagataggtt cactctctgt ccgcagctcg ttcccggccg agacgactgc 181 gccttcttcg gtgtcttcga tggcactgtt ggagatttcg ccagcgaaaa tgtgaaggat 241 cttgttgttc cacagttgat ttcctcgccc gcgtggcagg aggtgactga gatgctgaga 301 tcagacgtac ccgccactga ggtggacgag aagctccctc agttgcttga tcaggcagtc 361 gatgacatgt acaagaacgc agacaacgaa cttgtgaaga tgtgcgagca gcttaacaaa 421 gactacgcga gcagcacctc cgtcacggca gtcttggcca aaggcttcgt ggctgttggt 481 catctgggcg acagccgcat cgctatggga gtcgagacgc caaacgggtt gaactgcgag 541 ttcttgaccg ttgaccacaa gccggatatg ccacatgaga aactgcgcat catgcgcaat 601 ggaggcagtg ttgagtatct ccacaaccac aacaacaaac cgttcattcg aggtggtgac 661 ttctcgttcc ggaagtcgcg cggagagcag ccgatgcagc tccagtactc ccgagctttc 721 ggcgggaagg acctgaagat gtacggtttg agcaaccaac ccgacgtacg cgttgtccgc 781 gtcacgcctc aacaccgagt gatgattctc gcgactgatg gcttgtggga cgtcatgtct 841 gcggcgcaag ctgtagagat cgctatgcag gcacgacagg aaggaaggaa cccagcgcag 901 gcgctggtgg agatgaccct cgctgagcag cagagccgca accaaagtgc agacaacatt 961 actgcgatga cagtgttctt caagaagact gattag code AMINO ACID SEQUENCE: (Justin - is this the truncated sequence?? - Dr. B) code format="genbank"

code SLTMDVPPTIHVPLPPTSYPAFDAAIFTDIGGRKHQEDRFTLCPQLVPGRDDCAFFGVFDGTVGDFASENVKD code format="genbank"

code LVVPQLISSPAWQEVTEMLRSDVPATEVDEKLPQLLDQAVDDMYKNADNELVKMCEQLNKDYASSTSVTAVLA code format="genbank"

code KGFVAVGHLGDSRIAMGVETPNGLNCEFLTVDHKPDMPHEKLRIMRNGGSVEYLHNHNNKPFIRGGDFSFRKS code format="genbank"

code RGEQPMQLQYSRAFGGKDLKMYGLSNQPDVRVVRVTPQHRVMILATDGLWDVMSAAQAVEIAMQARQEGRNPA code format="genbank"

code QALVEMTLAEQQSRNQSADNTAMTVFFKKTD code format="genbank"

code PDB 2I44_A

ORGANISM: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">Yersinia enterocolitica GENE of INTEREST: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 32px; text-decoration: none; vertical-align: baseline;">phosphoanhydride phosphorylase code format="genbank"
 * Larry**

code NCBI GENE # or RefSeq#: <span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">4714245 EC# of Enzyme: 3.1.3.48 CDS GENE SEQUENCE: =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">ATGTCAGTTGCAAAGAGAAATCTGCACTTATCCGCACTCACTTTGATATTGGGCTGTTTTACCGCAGGTG = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CTGCCCCGATTGCTACACCGCCGGCCGGCTACACATTAGAGCGTGTGGTTATTTTGAGTCGACATGGTGT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TCGCTCCCCGACAAAACAAACCCAGCTAATGAATGATGTCACACCTGATAAATGGCCCCTGTGGCCAGTA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">AAAGCGGGCTATTTAACACCGCGAGGGGCCGAGTTAGTGACTTTGATGGGGGGATTTTATGGTGATTATT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TCCGCAGCCAAGGGTTGTTGTCTGCGGGGTGTCCGGTAGATGGCTCCGTTTATGCACAGGCAGATGTTGA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CCAACGAACCCGCTTAACCGGACAGGCATTCTTGGATGGGATCGCACCGGATTGTGGTCTGAAAGTACAT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TATCAGGCTGATTTGAAGAAAGTTGACCCGCTATTTCATACCGTCGAAGCGGGGGTCTGTAAACTGGACT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CAGCGAAAACTCATCAGGCTGTTGAGGAGCGATTGGGCGGGCCATTGAGTGATCTTAGCCAGCGCTATGC = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CAAACCCTTTGCTCAGATGGGCGAAGTGCTGAATTTTGCAGCATCGCCTTATTGCAAGTCATTGCAAAAA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">AATGGAAAAACCTGTGATTTTGCAACTTTTACGGCAAATGAAATTAAGGTAAACGAAGAAGGTACTAAAG = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TTTCTCTGAGTGGGCCATTGGCACTATCGTCGACATTGGGTGAAATTTTCCTGTTACAAAACTCACAAGC = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TATGCCGGATGTGGCCTGGCATCGGCTCAGCGGTGAAGAGAACTGGGTTTCGCTATTGTCGTTGCACAAT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">GCGCAATTTGATTTGATGGCCAAAACCCCGTATATCGCTCGCCATAAAGGGACCCCGCTGTTGCAACAAA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TTGATACGGCATTAGTGCTGCAACGCGATGCCCAAGGGCAAACACTGCCGCTGTCACCGCAAACCAAATT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">GCTGTTCCTCGGCGGGCATGACACCAATATTGCTAATATCGCTGGTATGTTAGGGGCCAATTGGCAATTA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CCACAGCAACCTGATAATACCCCGCCTGGTGGCGGATTAGTCTTTGAGCTATGGCAGAACCCAGATAATC = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">ATCAGCGCTATGTCGCCGTGAAAATGTTCTATCAAACGATGGATCAGCTGCGAAATGCCGAGAAATTAGA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TATGAAAAACAACCCAGCTAAAATTGTTCCAATTACCATTGAAGGTTGTGAGAACGAGGGTGATAACAAA = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">CTTTGCCAACTTGAGACTTTCCAAAAGAAAGTTGCCCAAGTGATAGAGCCAGCTTGCCATATTTAA = code format="genbank"

code AMINO ACID SEQUENCE: =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">MSVAKRNLHLSALTLILGCFTAGAAPIATPPAGYTLERVVILSRHGVRSPTKQTQLMNDV = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">TPDKWPLWPVKAGYLTPRGAELVTLMGGFYGDYFRSQGLLSAGCPVDGSVYAQADVDQRT = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">RLTGQAFLDGIAPDCGLKVHYQADLKKVDPLFHTVEAGVCKLDSAKTHQAVEERLGGPLS = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">DLSQRYAKPFAQMGEVLNFAASPYCKSLQKNGKTCDFATFTANEIKVNEEGTKVSLSGPL = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">ALSSTLGEIFLLQNSQAMPDVAWHRLSGEENWVSLLSLHNAQFDLMAKTPYIARHKGTPL = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">LQQIDTALVLQRDAQGQTLPLSPQTKLLFLGGHDTNIANIAGMLGANWQLPQQPDNTPPG = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">GGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDMKNNPAKIVPITIEGCENEGDNK = code format="genbank"

code =<span style="background-color: transparent; color: #000000; font-family: Arial; font-size: 14px; text-decoration: none; vertical-align: baseline;">LCQLETFQKKVAQVIEPACHI = code format="genbank"

code

__**Joey**__ ORGANISM: GENE of INTEREST: NCBI GENE # or RefSeq#: EC# of Enzyme: CDS GENE SEQUENCE: AMINO ACID SEQUENCE:

**NCBI GENE # or RefSeq#:** <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;"> 1255845 <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">ATGAAAAGTCGTTATTTAGTATTTTTTCTACCACTGATCGTAGCTAAATATACATCAGCAGAAACAGTGCAACCCTTTCATTCTCCTGAAGAAT <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">CAGTGAACAGTCAGTTCTACTTACCACCACCGCCAGGTAATGATGATCCGGCTTACCGCTATGATAAGGAGGCTTATTTTAAGGGCTATGCGA <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">TAAAGGGTTCCCCGCGATGGAAACAAGCTGCTGAGGATGCAGATGTAAGCGTGGAAAATATAGCCAGAATATTCTCGCCAGTAGTGGGTGCT <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">AAAATTAACCCCAAAGATACGCCAGAAACCTGGAATATGTTAAAGAATCTTCTGACAATGGGCGGCTACTACGCTACTGCTTCGGCAAAAAA <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">ATATTATATGCGTACCCGCCCCTTTGTCTTATTTAATCATTCCACCTGCCGTCCTGAAGATGAGAATACTTTGCGAAAAAATGGCTCTTACCCTT <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">CCGGGCATACTGCTTATGGTACACTTCTGGCATTAGTATTATCCGAGGCCAGACCGGAACGCGCGCAGGAGCTCGCCAGACGCGGATGGGAG <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">TTCGGGCAAAGCAGAGTGATATGCGGTGCTCACTGGCAAAGCGATGTTGATGCTGGCCGTTATGTGGGAGCAGTAGAGTTTGCAAGACTGCA <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">AACAATCCCGGCTTTTCAGAAGTCACTGGCAAAAGTCCGTGAGGAGCTGAACGACAAAAATAATTTATTGAGTAAAGAAGATCACCCCAAAC <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">TTAATTACTGA <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">>gi|16767569|ref|NP_463184.1| non-specific acid phosphatase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">MKSRYLVFFLPLIVAKYTSAETVQPFHSPEESVNSQFYLPPPPGNDDPAYRYDKEAYFKGYAIKGSPRWKQAAEDADVSVENIARIFSPVVGAKIN <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">PKDTPETWNMLKNLLTMGGYYATASAKKYYMRTRPFVLFNHSTCRPEDENTLRKNGSYPSGHTAYGTLLALVLSEARPERAQELARRGWEFGQS <span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">RVICGAHWQSDVDAGRYVGAVEFARLQTIPAFQKSLAKVREELNDKNNLLSKEDHPKLNY code format="genbank"
 * Krishna**
 * ORGANISM : **<span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">Salmonella
 * GENE of INTEREST: **<span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;">Acid phosphatase (PDB #2A96) (non essentiality)
 * EC# of Enzyme: **<span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-decoration: none; vertical-align: baseline;"> 3.1.3.2
 * CDS GENE SEQUENCE: **
 * AMINO ACID SEQUENCE: **

code code format="genbank"
 * PDB:**http://www.pdb.org/pdb/explore/remediatedSequence.do?structureId=2A96

code

__**Christina**__ code format="genbank"

code Notes: histidine phosphatase substrate non availability (not in Sigma) code format="genbank"

code **PDB:** [|PDB Structure] code format="genbank"

code


 * J.C.**

**Organism:**
Myobacterium tuberculosis Mycobacterium tuberculosis H37Rv (strain: H37Rv) 3.1.3.48
 * E.C. of Enzyme**:
 * Gene of Interest:**

Mycobacterium tuberculosis H37Rv
NCBI Reference Sequence: NC_000962.2 GenBank Graphics >gi|57116681:2507146-2507637 Mycobacterium tuberculosis H37Rv, complete genome GTGTCTGATCCGCTGCACGTCACATTCGTTTGTACGGGCAACATCTGCCGGTCGCCAATGGCCGAGAAGA TGTTCGCCCAACAGCTTCGCCACCGTGGCCTGGGTGACGCGGTGCGAGTGACCAGTGCGGGCACCGGGAA CTGGCATGTAGGCAGTTGCGCCGACGAGCGGGCGGCCGGGGTGTTGCGAGCCCACGGCTACCCTACCGAC CACCGGGCCGCACAAGTCGGCACCGAACACCTGGCGGCAGACCTGTTGGTGGCCTTGGACCGCAACCACG CTCGGCTGTTGCGGCAGCTCGGCGTCGAAGCCGCCCGGGTACGGATGCTGCGGTCATTCGACCCACGCTC GGGAACCCATGCGCTCGATGTCGAGGATCCCTACTATGGCGATCACTCCGACTTCGAGGAGGTCTTCGCC GTCATCGAATCCGCCCTGCCCGGCCTGCACGACTGGGTCGACGAACGTCTCGCGCGGAACGGACCGAGTT GA MptpA >1U2P:A|PDBID|CHAIN|SEQUENCE MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEH LAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARN GPS 1U2P code format="genbank"
 * CDS Gene Sequence**
 * Amino Acid Sequence**
 * PDB**

code

__**Indra**__

**Organism:** Shigella flexneri
code format="genbank"
 * Gene of Interest**: apyrase
 * NCBI Gene Number:** 876677 (periplasmic space,
 * E.C. Number of Enzyme**: 3.6.1.5
 * CDS Gene Sequence:**

code ATGAAAACCAAAAACTTTCTTCTTTTTTGTATTGCTACAAATATGATTTTTATCCCCTCAGCAAATGCTC TGAAGGCAGAAGGTTTTCTCACTCAACAAACTTCACCAGACAGTTTGTCAATACTTCCGCCGCCTCCGGC AGAGGATTCAGTAGTATTTCTGGCTGACAAAGCTCATTATGAATTCGGCCGCTCGCTCCGGGATGCTAAT CGTGTACGTCTCGCTAGCGAAGATGCATACTACGAGAATTTTGGTCTTGCATTTTCAGATGCTTATGGCA TGGATATTTCAAGGGAAAATACCCCAATCTTATATCAGTTGTTAACACAAGTACTACAGGATAGCCATGA TTACGCCGTGCGTAACGCCAAAGAATATTATAAAAGAGTTCGTCCATTCGTTATTTATAAAGACGCAACC TGTACACCTGATAAAGATGAGAAAATGGCTATCACTGGCTCTTATCCCTCTGGTCATGCATCCTTTGGTT GGGCAGTAGCACTGATACTTGCGGAGATTAATCCTCAACGTAAAGCGGAAATACTTCGACGTGGATATGA GTTTGGAGAAAGTCGGGTCATCTGCGGTGCGCATTGGCAAAGCGATGTAGAGGCTGGGCGTTTAATGGGA GCATCGGTTGTTGCAGTACTTCATAATACACCTGAATTTACCAAAAGCCTTAGCGAAGCCAAAAAAGAGT TTGAAGAATTAAATACTCCTACCAATGAACTGACCCCATAA code format="genbank"

code code format="genbank"
 * Amino Acid Sequence:**

code >gi|13448943|ref|NP_085159.1| apyrase [Shigella flexneri 5a] MKTKNFLLFCIATNMIFIPSANALKAEGFLTQQTSPDSLSILPPPPAEDSVVFLADKAHYEFGRSLRDAN RVRLASEDAYYENFGLAFSDAYGMDISRENTPILYQLLTQVLQDSHDYAVRNAKEYYKRVRPFVIYKDAT CTPDKDEKMAITGSYPSGHASFGWAVALILAEINPQRKAEILRRGYEFGESRVICGAHWQSDVEAGRLMG ASVVAVLHNTPEFTKSLSEAKKEFEELNTPTNELTP ~52% homology to a Escherichia blattae acid phosphatase 1D2T on PDB