Target-+Carbonic+Anhydrase+(Salmonella)

**ORGANISM : **Salmonella [enterica subsp. enterica serovar Enteritidis str. P125109]

**GENE of INTEREST: **Carbonic Anhydrase (PDB #3QY1)

**BACKGROUND/ DISEASE **

**IMAGE: **

**NCBI GENE # or RefSeq#**: 1251689 (undetermined essentiality)

**EC# OF ENZYME: ** 4.2.1.1

**CDS GENE SEQUENCE: ** <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">>gi|16763390:c202072-201410 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">ATGAAAGACATAGATACACTCATCAGCAACAATGCACTATGGTCAAAAATGCTGGTGGAAGAGGACCCCGGATTTTTTGAGAAACTGGCGCAAG <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">CGCAAAAACCGCGCTTTCTATGGATTGGATGTTCCGACAGCCGCGTTCCCGCAGAGCGTTTAACCGGGCTTGAACCGGGCGAATTGTTTGTTCA <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">CCGTAATGTGGCTAACCTGGTTATTCACACCGATCTGAACTGTCTCTCCGTGGTTCAGTATGCGGTAGATGTTCTGGAAGTTGAGCATATTATCATT <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">TGCGGCCACTCCGGTTGCGGCGGTATCAAGGCTGCGGTAGAAAACCCTGAGCTGGGCTTGATTAATAACTGGCTGCTGCATATCCGCGACATCTG <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">GCTTAAACATAGCTCGCTGTTGGGAAAAATGCCCGAAGAGCAACGTCTGGACGCGCTCTATGAATTGAACGTCATGGAACAGGTCTATAACCTGG <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">GGCATTCCACCATTATGCAGTCAGCGTGGAAACGCGGTCAGAATGTGACCATTCACGGCTGGGCGTACAGTATCAATGATGGCCTGCTGCGCGAT <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">CTTGACGTCACCGCCACCAACAGAGAAACGCTGGAGAACGGCTATCATAAGGGTATTTCCGCCCTAAGTCTGAAATACATTCCCCACCAATAA

<span style="font-family: 'Times New Roman',Times,serif;">**<span style="background-color: transparent; color: #000000; font-size: 16px; text-decoration: none; vertical-align: baseline;">OPTIMIZED GENE SEQUENCE USED IN LAB: ** <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">>filtered DNA sequence consisting of 663 bases. <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">ATGAAAGACATCGACACCCTGATCTCTAACAACGCGCTCTGGTCTAAGATGCTGGTTGAA <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">GAAGACCCGGGCTTCTTCGAGAAACTGGCGCAGGCGCAGAAACCGCGTTTCCTGTGGATC <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">GGTTGCTCTGACTCTCGTGTTCCGGCGGAACGTCTGACTGGTCTGGAACCGGGTGAACTG <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">TTCGTTCACCGTAATGTTGCGAACCTGGTTATCCACACCGACCTGAACTGCCTGTCTGTT <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">GTTCAGTACGCAGTTGATGTTCTGGAAGTTGAACACATCATCATCTGCGGTCACTCTGGT <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">TGCGGTGGTATCAAAGCGGCGGTTGAAAACCCGGAACTGGGCCTGATTAACAACTGGCTG <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">CTGCACATCCGTGACATCTGGCTGAAACACTCTTCTCTGCTGGGTAAAATGCCGGAAGAA <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">CAGCGTCTGGACGCGCTGTACGAGCTGAACGTAATGGAGCAGGTTTACAACCTGGGCCAC <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">TCTACCATCATGCAGTCTGCGTGGAAACGTGGTCAGAACGTTACCATCCACGGTTGGGCG <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">TACTCTATCAACGACGGTCTGCTGCGTGACCTGGACGTTACTGCGACCAATCGTGAAACC <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">CTGGAAAACGGTTACCACAAAGGTATCTCTGCGCTGTCTCTGAAATACATCCCGCACCAG <span style="font-family: 'Times New Roman',Times,serif;"> <span style="font-family: 'Times New Roman',Times,serif;">TAA <span style="font-family: 'Times New Roman',Times,serif;">

<span style="font-family: 'Times New Roman',Times,serif;">**<span style="background-color: transparent; color: #000000; font-size: 16px; text-decoration: none; vertical-align: baseline;">AMINO ACID SEQUENCE: ** <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">>gi|16763561|ref|NP_459176.1| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHS <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">GCGGIKAAVENPELGLINNWLLHIRDIWLKHSSLLGKMPEEQRLDALYELNVMEQVYNLGHSTIMQSAWKRGQNVTIHGWAYSINDGLLRDLDVTA <span style="background-color: transparent; color: #000000; font-family: 'Times New Roman',Times,serif; font-size: 16px; text-decoration: none; vertical-align: baseline;">TNRETLENGYHKGISALSLKYIPHQ


 * PDB:** http://www.pdb.org/pdb/explore/remediatedSequence.do?structureId=3QY1