TargetSp15+-+Thioredoxin+Reductase+(Listeria+monocytogenes)

==== ***/Disease Information (sort of like the Intro to your Mini Research Write up):** Listeriosis is a potentially fatal disease caused by the bacterial organism //Listeria monocytogenes//. It is unique from other bacterium, in that it can grow in colder temperatures. //L. monocytogenes,// in recent years, has been responsible for multiple small outbreaks of foodborne illnesses, many of which have resulted in fatalities. As a result, //L. monoctyogenes// is a growing concern to public health around the world. ====

==== Essential for the Thioredoxin system in multiple organisms. Thioredoxin system acts as a hydrogen donor to ribonucleotide reductase, which is essential for DNA synthesis. ([]) ====

==== “New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications” ( [] ) ====

Chain used for homology:
==== >4GCM:A|PDBID|CHAIN|SEQUENCE GMTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQ YGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEE GTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIG MKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA ====

==== MASEEKIYDVIIIGAGPAGMTAALYTSRADLDTLMIERGVPGGQMVNTAEVENYPGFDSI LGPDLSDKMLSGAKQFGAEYAYGDIKEVVDGKEFKTVTAGSKTYKARAIIIATGAEHRKL GAAGEEELSGRGVSYCAVCDGAFFKNRELIVVGGGDSAVEEGTYLTRYADKVTIVHRRDK LRAQQILQDRAFKDEKVDFIWNSTVEEIVGDGKKVTGAKLVSTVDGSESIMPVDGVFIYV GLVPLTKAFLNLGITDDEGYIVTDEEMRTNLPGIFAAGDVRAKSLRQIVTATGDGGLAGQ NAQKYVEELKESLEAEAAK ====

ATGGCTAGTGAAGAAAAAATTTATGATGTGATTATTATTGGGGCGGGGCCTGCTGGAATGACAGCAGCTT
==== TATATACTTCCCGTGCAGATTTAGATACGTTAATGATTGAACGCGGTGTACCCGGTGGACAAATGGTTAA CACAGCTGAGGTAGAAAATTACCCAGGATTTGATAGCATTTTAGGACCAGATTTGTCCGACAAGATGCTT AGTGGTGCGAAACAATTTGGAGCTGAGTATGCTTATGGTGATATTAAAGAAGTTGTTGACGGTAAAGAAT TTAAAACAGTAACAGCTGGGTCGAAAACCTACAAGGCTCGGGCAATTATTATTGCGACTGGAGCTGAACA CCGTAAACTTGGCGCGGCTGGTGAAGAAGAACTTAGTGGACGTGGTGTTTCTTACTGCGCAGTCTGTGAC GGAGCATTCTTCAAAAATCGCGAATTAATTGTGGTTGGCGGCGGAGACTCTGCAGTGGAAGAAGGAACCT ACTTGACTCGTTATGCAGATAAAGTAACCATTGTACACCGTCGTGATAAATTGCGAGCACAACAAATTTT ACAAGATCGTGCTTTTAAAGATGAAAAAGTTGATTTCATTTGGAATAGTACAGTAGAAGAAATTGTTGGC GATGGTAAAAAAGTAACAGGAGCAAAACTTGTTTCTACTGTGGATGGCTCCGAATCGATTATGCCAGTAG ATGGCGTTTTCATCTATGTTGGACTTGTTCCACTTACGAAAGCATTCTTAAATTTAGGTATTACAGATGA TGAAGGATACATCGTAACGGACGAAGAAATGCGTACAAATCTTCCTGGTATTTTTGCAGCAGGTGATGTT CGTGCGAAAAGCTTACGCCAAATTGTAACAGCTACAGGCGACGGCGGACTTGCTGGACAAAATGCTCAAA ====